LigandTracer® monitors molecular interactions in real-time, right on your lab bench, with only a few preparatory steps and limited input.

The most common target is a cellular receptor expressed on the surface of living cells, but almost any interaction can be monitored as long as:

  • You can label your ligand of interest
  • Targets can be attached to a Petri dish
  • The interaction occurs within minutes to hours

LigandTracer monitors interactions as they happen; detecting interaction properties that can easily be missed by using established endpoint methods such as ELISA. Data points are taken automatically at set intervals, allowing you to obtain in-depth information about the interaction that you’re studying.

Key features

  • Estimate the affinity and kinetics of interactions with living cells
  • Use regular Petri dishes of any brand (Ø:87-89 mm and h: 15-18 mm without the lid)
  • Measure at room temperature, in incubators, or in cold rooms
  • Plan your run and store relevant information with our intuitive control software
  • Estimate interaction parameters with our versatile evaluation tool TraceDrawer
  • Quickly advance your knowledge with LigandTracer Learning

LigandTracer Green

Detects fluorescence. Three interchangable detectors available:

  • Blue – Green: 488 nm – 535 nm (em/ex), e.g. FITC and Alexa 488
  • Yellow – Red: 590 nm – 632 nm (em/ex), e.g. Rhodamine Red
  • Red – NIR: 632 nm – 670 nm (em/ex), e.g. Alexa Fluor 633

LigandTracer Green is compatible with LigandTracer MultiDish 2×2, which allows you to run two separate experiments at identical conditions in parallel.

Ligand Tracer Yellow

Detects high energy ɣ radiation, e.g 99mTc, 11C, 111In, 177Lu, 18F, 89Zr, 188Re and 68Ga.

LigandTracer White

Detects β radiation, e.g. 18F, 14C, 35S, 11C.

LigandTracer Grey

Detects low energy ɣ radiation, e.g. 125I.

Documents

Application Notes

  • Technology-note Blue-Lime-detector

    Download (280.46 kB)
  • Application Note - LigandTracer - Detecting Real-time DNA Synthesis Using LigandTracer White

    Download (315.42 kB)
  • Application Note - LigandTracer - LigandTracer MultiDish Increasing Throughput And Simplifying Comparison

    Download (436.6 kB)
  • Application Note - LigandTracer - Monitoring Protein-tissue Interactions In Real-time

    Download (330.63 kB)

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